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5-Amino-1MQ 50 mg research-grade lyophilized powder in a glass vial. This small-molecule compound, 5-amino-1-methylquinolinium, is investigated in experimental models as a selective inhibitor of the enzyme nicotinamide N-methyltransferase (NNMT) and a modulator of NAD+ salvage and SAM-cycle metabolism.

Research Use Only: All products are intended exclusively for laboratory and scientific research. Not for human or veterinary use.

Purity
High-purity research grade

Form
Lyophilized powder

Content
50 mg 5-Amino-1MQ per vial

Packaging
Glass vial with sterile closure

Storage
Store lyophilized at 2−8 °C (desiccated, protect from light)

Molecular formula
C10H11N2 (Iodide salt)

Molecular weight
~274.11 g·mol⁻¹ (Iodide salt)

IUPAC Name
5-amino-1-methylquinolin-1-ium iodide

CAS number
42464-96-0
In laboratory workflows, lyophilized research peptides are typically handled with suitable sterile diluents such as bacteriostatic water (BAC). For a compatible research-only solvent, see Bacteriostatic water – 10 ml .

Research Overview

5-Amino-1MQ is a selective inhibitor of nicotinamide N-methyltransferase (NNMT), used in laboratory studies to probe mechanisms of cellular energy metabolism, NAD+ salvage and S-adenosylmethionine (SAM) cycle flux. :contentReference[oaicite:5]{index=5}

Primary Research Areas

  • NNMT inhibition & NAD+ metabolism: Experimental models exploring NNMT blockade and downstream NAD+ and SAM-cycle modulation.
  • Adipocyte energy metabolism & lipogenesis suppression: In vivo models of diet-induced obesity where 5-Amino-1MQ reduces lipogenesis and methylation marker levels.
  • Methylation burden & metabolic dysfunction research: Laboratory applications in cellular methylation stress, SAM-cycle imbalance and NAD+ salvage engineering.

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