{"id":22946,"date":"2026-03-11T19:36:15","date_gmt":"2026-03-11T19:36:15","guid":{"rendered":"https:\/\/limitlesscyprus.com\/?post_type=product&#038;p=22946"},"modified":"2026-07-15T11:59:40","modified_gmt":"2026-07-15T09:59:40","slug":"methylene-blue-5mg-60-capsules-el","status":"publish","type":"product","link":"https:\/\/limitlesscyprus.com\/el\/product\/methylene-blue-5mg-60-capsules-el\/","title":{"rendered":"Methylene Blue 5 mg &#8211; 60 \u03ba\u03ac\u03c8\u03bf\u03c5\u03bb\u03b5\u03c2"},"content":{"rendered":"<div style=\"font-family: 'R\u03ba\u03b1\u03b9om Grotesque St\u03ba\u03b1\u03b9ard','Poppins',sans-serif; font-size: 14.5px; color: #061735; line-height: 1.6;\">\n<p><!-- Intro --><\/p>\n<p style=\"margin-bottom: 12px;\"><strong style=\"font-family: 'R\u03ba\u03b1\u03b9om Grotesque Bold','Poppins',sans-serif;\">\u039a\u03c5\u03b1\u03bd\u03cc \u03c4\u03bf\u03c5 \u03bc\u03b5\u03b8\u03c5\u03bb\u03b5\u03bd\u03af\u03bf\u03c5 5 mg \u2014 60 \u03b5\u03c1\u03b5\u03c5\u03bd\u03b7\u03c4\u03b9\u03ba\u03ad\u03c2 \u03ba\u03ac\u03c8\u03bf\u03c5\u03bb\u03b5\u03c2 \u03c6\u03b1\u03c1\u03bc\u03b1\u03ba\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae\u03c2 \u03c0\u03bf\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2.<\/strong> Methylene blue holds a unique position in the history of pharmacology: it was the first synthetic drug ever used in humans (Ehrlich, 1891), the founding lead compound of every phenothiazine antipsychotic, the parent scaffold of every methylene-bridged tau aggregation inhibitor, \u03ba\u03b1\u03b9 the gold-st\u03ba\u03b1\u03b9ard antidote for methemoglobinemia. In neuroscience, it has emerged over the past two decades as the most extensively characterized low-dose mitochondrial enhancer, with controlled human imaging studies demonstrating measurable effects on brain glucose metabolism, BOLD response \u03ba\u03b1\u03b9 functional memory at doses an order of magnitude below the antimethemoglobinemia range. The 5 mg per-capsule format corresponds precisely to the low-dose nootropic \u03ba\u03b1\u03b9 mitochondrial-enhancement window characterized in published clinical pharmacology.<\/p>\n<p><!-- \u0391\u03c0\u03bf\u03ba\u03bb\u03b5\u03b9\u03c3\u03c4\u03b9\u03ba\u03ac \u03b3\u03b9\u03b1 \u03b5\u03c1\u03b5\u03c5\u03bd\u03b7\u03c4\u03b9\u03ba\u03ae \u03c7\u03c1\u03ae\u03c3\u03b7 box --><\/p>\n<div style=\"border-left: 4px solid #0075ED; background: #F5FAFF; padding: 10px 12px; border-radius: 10px; margin-bottom: 14px; color: #061735; font-family: 'R\u03ba\u03b1\u03b9om Grotesque St\u03ba\u03b1\u03b9ard','Poppins',sans-serif;\"><strong style=\"font-family: 'R\u03ba\u03b1\u03b9om Grotesque Bold','Poppins',sans-serif;\">\u0391\u03a0\u039f\u039a\u039b\u0395\u0399\u03a3\u03a4\u0399\u039a\u0391 \u0393\u0399\u0391 \u0395\u03a1\u0395\u03a5\u039d\u0397\u03a4\u0399\u039a\u0397 \u03a7\u03a1\u0397\u03a3\u0397<\/strong> \u00a0\u00b7\u00a0 \u0394\u03b5\u03bd \u03c0\u03c1\u03bf\u03bf\u03c1\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b3\u03b9\u03b1 \u03b1\u03bd\u03b8\u03c1\u03ce\u03c0\u03b9\u03bd\u03b7 \u03ae \u03ba\u03c4\u03b7\u03bd\u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u03c7\u03c1\u03ae\u03c3\u03b7. \u039c\u03cc\u03bd\u03bf \u03b3\u03b9\u03b1 \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03bf\u03cd\u03c2 \u03ba\u03b1\u03b9 \u03c3\u03c5\u03bb\u03bb\u03b5\u03ba\u03c4\u03b9\u03ba\u03bf\u03cd\u03c2 \u03c3\u03ba\u03bf\u03c0\u03bf\u03cd\u03c2.<\/div>\n<p><!-- Gradient spec card --><\/p>\n<div style=\"font-family: 'R\u03ba\u03b1\u03b9om Grotesque St\u03ba\u03b1\u03b9ard','Poppins',sans-serif; border-radius: 16px; overflow: hidden; box-shadow: 0 2px 0 rgba(6,23,53,0.12); background: linear-gradient(135deg,#00B4FF 0%,#0075ED 100%); color: #f4f2e9; margin: 18px 0;\">\n<div style=\"padding: 15px 20px;\">\n<div style=\"display: flex; border-bottom: 1px solid rgba(251,250,246,0.35);\">\n<div style=\"flex: 1; padding: 10px 14px; color: #fbfaf6;\">\u039a\u03b1\u03b8\u03b1\u03c1\u03cc\u03c4\u03b7\u03c4\u03b1<\/div>\n<div style=\"flex: 2; padding: 10px 14px;\">\u2265 99 % USP \u2014 \u03c6\u03b1\u03c1\u03bc\u03b1\u03ba\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae \u03c0\u03bf\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1, \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 \u03b1\u03c0\u03cc \u03b1\u03bd\u03b5\u03be\u03ac\u03c1\u03c4\u03b7\u03c4\u03bf \u03c6\u03bf\u03c1\u03ad\u03b1, CoA \u03b4\u03b9\u03b1\u03b8\u03ad\u03c3\u03b9\u03bc\u03bf<\/div>\n<\/div>\n<div style=\"display: flex; border-bottom: 1px solid rgba(251,250,246,0.35);\">\n<div style=\"flex: 1; padding: 10px 14px; color: #fbfaf6;\">\u039c\u03bf\u03c1\u03c6\u03ae<\/div>\n<div style=\"flex: 2; padding: 10px 14px;\">\u0395\u03c1\u03b5\u03c5\u03bd\u03b7\u03c4\u03b9\u03ba\u03ad\u03c2 \u03ba\u03ac\u03c8\u03bf\u03c5\u03bb\u03b5\u03c2<\/div>\n<\/div>\n<div style=\"display: flex; border-bottom: 1px solid rgba(251,250,246,0.35);\">\n<div style=\"flex: 1; padding: 10px 14px; color: #fbfaf6;\">\u03a0\u03b5\u03c1\u03b9\u03b5\u03c7\u03cc\u03bc\u03b5\u03bd\u03bf<\/div>\n<div style=\"flex: 2; padding: 10px 14px;\">5 mg \u03ba\u03c5\u03b1\u03bd\u03cc \u03c4\u03bf\u03c5 \u03bc\u03b5\u03b8\u03c5\u03bb\u03b5\u03bd\u03af\u03bf\u03c5 (\u03c4\u03c1\u03b9\u03ad\u03bd\u03c5\u03b4\u03c1\u03bf \u03c7\u03bb\u03c9\u03c1\u03af\u03b4\u03b9\u03bf) \u03b1\u03bd\u03ac \u03ba\u03ac\u03c8\u03bf\u03c5\u03bb\u03b1<\/div>\n<\/div>\n<div style=\"display: flex; border-bottom: 1px solid rgba(251,250,246,0.35);\">\n<div style=\"flex: 1; padding: 10px 14px; color: #fbfaf6;\">\u03a3\u03cd\u03bd\u03bf\u03bb\u03bf<\/div>\n<div style=\"flex: 2; padding: 10px 14px;\">60 \u03ba\u03ac\u03c8\u03bf\u03c5\u03bb\u03b5\u03c2 per bottle (300 mg total)<\/div>\n<\/div>\n<div style=\"display: flex; border-bottom: 1px solid rgba(251,250,246,0.35);\">\n<div style=\"flex: 1; padding: 10px 14px; color: #fbfaf6;\">\u03a3\u03c5\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03af\u03b1<\/div>\n<div style=\"flex: 2; padding: 10px 14px;\">\u03a3\u03c6\u03c1\u03b1\u03b3\u03b9\u03c3\u03bc\u03ad\u03bd\u03b7 \u03c6\u03b9\u03ac\u03bb\u03b7 \u03bc\u03b5 \u03c0\u03ce\u03bc\u03b1 \u03b1\u03c3\u03c6\u03b1\u03bb\u03b5\u03af\u03b1\u03c2<\/div>\n<\/div>\n<div style=\"display: flex; border-bottom: 1px solid rgba(251,250,246,0.35);\">\n<div style=\"flex: 1; padding: 10px 14px; color: #fbfaf6;\">\u0391\u03c0\u03bf\u03b8\u03ae\u03ba\u03b5\u03c5\u03c3\u03b7<\/div>\n<div style=\"flex: 2; padding: 10px 14px;\">\u0398\u03b5\u03c1\u03bc\u03bf\u03ba\u03c1\u03b1\u03c3\u03af\u03b1 \u03b4\u03c9\u03bc\u03b1\u03c4\u03af\u03bf\u03c5, \u03be\u03b7\u03c1\u03cc, \u03c0\u03c1\u03bf\u03c3\u03c4\u03b1\u03c4\u03b5\u03c5\u03bc\u03ad\u03bd\u03bf \u03b1\u03c0\u03cc \u03c4\u03bf \u03c6\u03c9\u03c2<\/div>\n<\/div>\n<div style=\"display: flex; border-bottom: 1px solid rgba(251,250,246,0.35);\">\n<div style=\"flex: 1; padding: 10px 14px; color: #fbfaf6;\">\u039c\u03bf\u03c1\u03b9\u03b1\u03ba\u03cc\u03c2 \u03c4\u03cd\u03c0\u03bf\u03c2<\/div>\n<div style=\"flex: 2; padding: 10px 14px;\">C\u2081\u2086H\u2081\u2088ClN\u2083S\u00b73H\u2082O (\u03c4\u03c1\u03b9\u03ad\u03bd\u03c5\u03b4\u03c1\u03bf)<\/div>\n<\/div>\n<div style=\"display: flex; border-bottom: 1px solid rgba(251,250,246,0.35);\">\n<div style=\"flex: 1; padding: 10px 14px; color: #fbfaf6;\">\u039c\u03bf\u03c1\u03b9\u03b1\u03ba\u03cc \u03b2\u03ac\u03c1\u03bf\u03c2<\/div>\n<div style=\"flex: 2; padding: 10px 14px;\">\u2248 373.90 g\u00b7mol\u207b\u00b9<\/div>\n<\/div>\n<div style=\"display: flex; border-bottom: 1px solid rgba(251,250,246,0.35);\">\n<div style=\"flex: 1; padding: 10px 14px; color: #fbfaf6;\">\u039f\u03bd\u03bf\u03bc\u03b1\u03c3\u03af\u03b1 IUPAC<\/div>\n<div style=\"flex: 2; padding: 10px 14px;\">[7-(dimethylamino)phenothiazin-3-ylidene]-dimethylazanium chloride trihydrate<\/div>\n<\/div>\n<div style=\"display: flex; border-bottom: 1px solid rgba(251,250,246,0.35);\">\n<div style=\"flex: 1; padding: 10px 14px; color: #fbfaf6;\">\u0391\u03c1\u03b9\u03b8\u03bc\u03cc\u03c2 CAS<\/div>\n<div style=\"flex: 2; padding: 10px 14px;\">61-73-4 (\u03ac\u03bd\u03c5\u03b4\u03c1\u03bf)\u00b7 7220-79-3 (\u03c4\u03c1\u03b9\u03ad\u03bd\u03c5\u03b4\u03c1\u03bf)<\/div>\n<\/div>\n<div style=\"display: flex;\">\n<div style=\"flex: 1; padding: 10px 14px; color: #fbfaf6;\">\u03a3\u03c5\u03bd\u03ce\u03bd\u03c5\u03bc\u03b1<\/div>\n<div style=\"flex: 2; padding: 10px 14px;\">Methylthioninium chloride; basic blue 9; ProvayBlue<\/div>\n<\/div>\n<\/div>\n<\/div>\n<p><!-- \u0395\u03c0\u03b9\u03c3\u03ba\u03cc\u03c0\u03b7\u03c3\u03b7 \u03ad\u03c1\u03b5\u03c5\u03bd\u03b1\u03c2 --><\/p>\n<h3 style=\"font-size: 16.5px; font-weight: 800; margin: 12px 0 6px; font-family: 'R\u03ba\u03b1\u03b9om Grotesque Bold','Poppins',sans-serif;\">\u0395\u03c0\u03b9\u03c3\u03ba\u03cc\u03c0\u03b7\u03c3\u03b7 \u03ad\u03c1\u03b5\u03c5\u03bd\u03b1\u03c2<\/h3>\n<p style=\"margin: 0 0 10px;\">Methylene blue (methylthioninium chloride) is a phenothiazine dye with an extraordinary range of well-characterized pharmacology, dose-dependent \u03ba\u03b1\u03b9 frequently U-shaped [1]. At low concentrations (\u2264 1 mg\/kg), it acts as an alternative electron carrier in the mitochondrial electron transport chain \u2014 accepting electrons from NADH \u03ba\u03b1\u03b9 donating them directly to cytochrome c \u2014 bypassing complex I\/III blockades \u03ba\u03b1\u03b9 increasing cellular ATP production \u03ba\u03b1\u03b9 oxygen consumption rate [1,2]. At slightly higher concentrations it inhibits monoamine oxidase \u03ba\u03b1\u03b9 tau aggregation, \u03ba\u03b1\u03b9 at clinical-antidote concentrations it reduces methemoglobin to hemoglobin via the NADPH-dependent diaphorase pathway. Functional human imaging at 0.5\u20134 mg\/kg shows increased cerebral glucose metabolism, BOLD response in memory-related circuits, \u03ba\u03b1\u03b9 improved performance on declarative-memory tasks [3]. The molecule has a &gt; 130-year clinical safety history, with the principal contraindications well-mapped (G6PD deficiency; concurrent serotonergic agents).<\/p>\n<p><!-- \u039a\u03cd\u03c1\u03b9\u03bf\u03b9 \u03c4\u03bf\u03bc\u03b5\u03af\u03c2 \u03ad\u03c1\u03b5\u03c5\u03bd\u03b1\u03c2 --><\/p>\n<h4 style=\"font-size: 15px; font-weight: bold; margin: 10px 0 5px; font-family: 'R\u03ba\u03b1\u03b9om Grotesque Bold','Poppins',sans-serif;\">\u039a\u03cd\u03c1\u03b9\u03bf\u03b9 \u03c4\u03bf\u03bc\u03b5\u03af\u03c2 \u03ad\u03c1\u03b5\u03c5\u03bd\u03b1\u03c2<\/h4>\n<ul style=\"margin: 0 0 10px 18px; padding-left: 18px; font-family: 'R\u03ba\u03b1\u03b9om Grotesque St\u03ba\u03b1\u03b9ard','Poppins',sans-serif;\">\n<li style=\"margin: 4px 0;\"><strong style=\"font-family: 'R\u03ba\u03b1\u03b9om Grotesque Bold','Poppins',sans-serif;\">\u039c\u03b9\u03c4\u03bf\u03c7\u03bf\u03bd\u03b4\u03c1\u03b9\u03b1\u03ba\u03ae \u03b2\u03b9\u03bf\u03b5\u03bd\u03b5\u03c1\u03b3\u03b7\u03c4\u03b9\u03ba\u03ae \u03ba\u03b1\u03b9 electron-transport bypass<\/strong> \u2014 the canonical small molecule for studying alternative-electron-carrier pharmacology \u03ba\u03b1\u03b9 rescue of complex-I-deficient phenotypes [1,2].<\/li>\n<li style=\"margin: 4px 0;\"><strong style=\"font-family: 'R\u03ba\u03b1\u03b9om Grotesque Bold','Poppins',sans-serif;\">Cognitive \u03ba\u03b1\u03b9 memory research<\/strong> \u2014 controlled human fMRI\/PET studies show enhanced memory-task performance \u03ba\u03b1\u03b9 increased brain glucose metabolism at low-dose ranges [3].<\/li>\n<li style=\"margin: 4px 0;\"><strong style=\"font-family: 'R\u03ba\u03b1\u03b9om Grotesque Bold','Poppins',sans-serif;\">Tauopathy \u03ba\u03b1\u03b9 neurodegeneration<\/strong> \u2014 the parent scaffold for hydromethylthionine \u03ba\u03b1\u03b9 a workhorse tool in tau-aggregation assays; investigated in AD, FTD \u03ba\u03b1\u03b9 PSP models [1].<\/li>\n<li style=\"margin: 4px 0;\"><strong style=\"font-family: 'R\u03ba\u03b1\u03b9om Grotesque Bold','Poppins',sans-serif;\">Mood \u03ba\u03b1\u03b9 psychiatric research<\/strong> \u2014 studied in bipolar depression \u03ba\u03b1\u03b9 major depressive disorder, leveraging dose-dependent MAO-A inhibition \u03ba\u03b1\u03b9 mitochondrial enhancement [1].<\/li>\n<li style=\"margin: 4px 0;\"><strong style=\"font-family: 'R\u03ba\u03b1\u03b9om Grotesque Bold','Poppins',sans-serif;\">Methemoglobinemia \u03ba\u03b1\u03b9 oxidative-redox research<\/strong> \u2014 the gold-st\u03ba\u03b1\u03b9ard antidote \u03ba\u03b1\u03b9 a robust probe of NADPH-diaphorase activity, G6PD-deficiency phenotypes \u03ba\u03b1\u03b9 free-radical biology [1].<\/li>\n<\/ul>\n<p><!-- \u0392\u03b9\u03b2\u03bb\u03b9\u03bf\u03b3\u03c1\u03b1\u03c6\u03af\u03b1 --><\/p>\n<h4 style=\"font-size: 15px; font-weight: bold; margin: 10px 0 5px; font-family: 'R\u03ba\u03b1\u03b9om Grotesque Bold','Poppins',sans-serif;\">\u0392\u03b9\u03b2\u03bb\u03b9\u03bf\u03b3\u03c1\u03b1\u03c6\u03af\u03b1<\/h4>\n<ol style=\"margin: 0 0 10px 18px; padding-left: 18px; font-family: 'R\u03ba\u03b1\u03b9om Grotesque St\u03ba\u03b1\u03b9ard','Poppins',sans-serif;\">\n<li style=\"margin: 4px 0;\">Tucker D, Lu Y, Zhang Q. From mitochondrial function to neuroprotection \u2014 an emerging role for methylene blue. Mol Neurobiol. 2018;55(6):5137\u20135153.<\/li>\n<li style=\"margin: 4px 0;\">Atamna H, Nguyen A, Schultz C, et al. Methylene blue delays cellular senescence \u03ba\u03b1\u03b9 enhances key mitochondrial biochemical pathways. FASEB J. 2008;22(3):703\u2013712.<\/li>\n<li style=\"margin: 4px 0;\">Rodriguez P, Zhou W, Barrett DW, et al. Multimodal r\u03ba\u03b1\u03b9omized functional MR imaging of the effects of methylene blue in the human brain. Radiology. 2016;281(2):516\u2013526.<\/li>\n<\/ol>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u039a\u03c5\u03b1\u03bd\u03cc \u03c4\u03bf\u03c5 \u03bc\u03b5\u03b8\u03c5\u03bb\u03b5\u03bd\u03af\u03bf\u03c5 5 mg \u2014 60 \u03b5\u03c1\u03b5\u03c5\u03bd\u03b7\u03c4\u03b9\u03ba\u03ad\u03c2 \u03ba\u03ac\u03c8\u03bf\u03c5\u03bb\u03b5\u03c2 \u03c6\u03b1\u03c1\u03bc\u03b1\u03ba\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae\u03c2 \u03c0\u03bf\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2. Methylene blue holds a unique position in the history [&hellip;]<\/p>\n","protected":false},"featured_media":4217,"comment_status":"closed","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"_lb_product_label_url":"https:\/\/drive.google.com\/file\/d\/1Y4EikfxJxiblUsgAMqdCReJMLOeFihYa\/view?usp=drive_link","_lb_product_label_size":"150x50","_lb_product_label_width":"150","_lb_product_label_height":"50"},"product_brand":[41],"product_cat":[1167,1158,1168,1155],"product_tag":[],"class_list":["post-22946","product","type-product","status-publish","has-post-thumbnail","product_brand-limitlessbiochem","product_cat-1167","product_cat-1158","product_cat-1168","product_cat-1155","desktop-align-left","tablet-align-left","mobile-align-left","first","instock","purchasable","product-type-simple","product-backorders-allowed"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.1 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Methylene Blue 5 mg \u2013 60 capsules | Limitless BioChem<\/title>\n<meta name=\"description\" content=\"Purchase Methylene Blue 5 mg research capsules (60-count bottle). 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